Quantification of turbate microstructures through a subglacial till : dimensions and characteristics

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Evaluation of existing and new methods of tracking glacier terminus change

ACKNOWLEDGEMENTS The authors thank two anonymous reviewers for constructive comments that helped to improve the manuscript. This research was financially supported by J.M.L.’s PhD funding from UK Natural Environment Research Council grant No. NE/I528742/1.Peer reviewedPublisher PD

Google Earth Engine Digitisation Tool (GEEDiT), and Margin change Quantification Tool (MaQiT) - simple tools for the rapid mapping and quantification of changing Earth surface margins

Changes in margins derived from satellite imagery are quantitative indicators of the environmental processes and drivers acting on the Earth's surface, for example retreating ice margins or coastal changes with rising sea level. However, the large-scale rapid visualisation and analysis of the satellite record is often impractical due to factors such as computer processing power, software availability, internet connection speed and/or user expertise in remote sensing. Here are presented three new, freely accessible tools that together can be used to process, visualise and review data from the full Landsat 4–8 and Sentinel 1–2 satellite records in seconds, enabling efficient mapping (through manual digitisation) and automated quantification of margin changes. These tools are highly accessible for users from a range of remote-sensing expertise (from academics to high school students), with minimal computational, licensing and knowledge-based barriers to access. The Google Earth Engine Digitisation Tool (GEEDiT) allows users to define a point anywhere on the planet and filter data from each satellite for user-defined time frames, maximum acceptable cloud cover extent, and options of predefined or custom image band combinations via a simple graphical user interface (GUI). GEEDiT allows georeferenced vectors to be easily and rapidly mapped from each image, with image metadata and user notes automatically appended to each vector, which can then be exported for subsequent analysis. The GEEDiT Reviewer tool allows users to quality control their own/others' data and also filter existing datasets based on the spatial/temporal requirements for their particular research question. The Margin change Quantification Tool (MaQiT) is complementary to GEEDiT and GEEDiT Reviewer, allowing the rapid quantification of these margin changes by utilising two well-established methods that have previously been used to measure glacier margin change and two new methods via a similarly simple GUI. A case study of the lake-terminating glacier Breiðamerkurjökull, Iceland, is used to demonstrate the complementary functionality of GEEDiT, GEEDiT Reviewer and MaQiT, though it should be noted that MaQiT is also suitable for the (re-)analysis of existing datasets not generated by GEEDiT. MaQiT has been developed with the original aim of quantifying tidewater glacier terminus change, though the methods included within the tool have potential for wide applications in multiple areas of Earth surface science (e.g. coastal and vegetation extent change). It is hoped that these tools will allow a wide range of researchers and students across the geosciences to efficiently map, analyse and access volumes of data that would have previously proven prohibitive

On the Classification of UGC1382 as a Giant Low Surface Brightness Galaxy

We provide evidence that UGC1382, long believed to be a passive elliptical galaxy, is actually a giant low surface brightness (GLSB) galaxy which rivals the archetypical GLSB Malin 1 in size. Like other GLSB galaxies, it has two components: a high surface brightness disk galaxy surrounded by an extended low surface brightness (LSB) disk. For UGC1382, the central component is a lenticular system with an effective radius of 6 kpc. Beyond this, the LSB disk has an effective radius of ~38 kpc and an extrapolated central surface brightness of ~26 mag/arcsec^2. Both components have a combined stellar mass of ~8x10^10 M_sun, and are embedded in a massive (10^10 M_sun) low-density (<3 M_sun/pc^2) HI disk with a radius of 110 kpc, making this one of the largest isolated disk galaxies known. The system resides in a massive dark matter halo of at least 2x10^12 M_sun. Although possibly part of a small group, its low density environment likely plays a role in the formation and retention of the giant LSB and HI disks. We model the spectral energy distributions and find that the LSB disk is likely older than the lenticular component. UGC1382 has UV-optical colors typical of galaxies transitioning through the green valley. Within the LSB disk are spiral arms forming stars at extremely low efficiencies. The gas depletion time scale of ~10^11 yr suggests that UGC1382 may be a very long term resident of the green valley. We find that the formation and evolution of the LSB disk is best explained by the accretion of gas-rich LSB dwarf galaxies.Comment: 17 pages, 16 figures, 4 tables; accepted to the Astrophysical Journa

Stepping On Fall Prevention Project

Background: Falls are a major problem in the United States among the older adult population and provide opportunity for community outreach via student-led physical therapy projects. Objective: The purpose of this project was to investigate the relationship between fall related outcome measures and questionnaires with the completion of the Stepping On Fall Prevention program along with evaluating the benefits of Physical Therapy student development with participation in service learning projects. Methods: The research quantified the fall risk of 13 participants with assessment of: gait speed (Timed Up and Go), lower extremity strength (30-Second Chair Stand), balance (4-Stage Balance Test), and psychological factors (Stay Independent Questionnaire, Falls Efficacy Scale-International, and Geriatric Depression Scale). Results: Of the functional measures, significant improvements were observed in the Timed up and Go (TUG) (∆1.72s ± 1.66, p=0.003), the 30-second chair stand (∆4.54 ± 4.27, p= 0.002), Stage 4 of the 4-Stage Balance Test (∆3.37s ± 3.26, p= 0.003), and the Stay Independent questionnaire (∆1.77 ± 2.52, p=0.026). Conclusion: Stepping On demonstrated improvements in gait speed, strength, and balance. These improvements allow older adults to improve their overall safety in both their own homes and the community. More research is needed to evaluate the psychological benefits of completing Stepping On. Furthermore, service learning project opportunities should become more of a standard practice across physical therapy programs

The glacial geomorphology of upper Godthåbsfjord (Nuup Kangerlua) in south-west Greenland

© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of Journal of Maps. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.The Greenland Ice Sheet (GrIS) is known to have experienced widespread retreat over the last century. Information on outlet glacier dynamics, prior to this, are limited due to both a lack of observations and a paucity of mapped or mappable deglacial evidence which restricts our understanding of centennial to millennial timescale dynamics of the GrIS. Here we present glacial geomorphological mapping, for upper Godthåbsfjord, covering 5800 km 2 at a scale of 1:92,000, using a combination of ASTER GDEM V2, a medium-resolution DEM (error < 10 m horizontal and < 6 m vertical accuracy), panchromatic orthophotographs and ground truthing. This work provides a detailed geomorphological assessment for the area, compiled as a single map, comprising of moraines, meltwater channels, streamlined bedrock, sediment lineations, ice-dammed lakes, trimlines, terraces, gullied sediment and marine limits. Whilst some of the landforms have been previously identified, the new information presented here improves our understanding of ice margin behaviour and can be used for future numerical modelling and landform dating programmes. Data also form the basis for palaeoglaciological reconstructions and contribute towards understanding of the centennial to millennial timescale record of this sector of the GrIS.Peer reviewedFinal Published versio

CaMKII-dependent responses to ischemia and reperfusion challenges in the heart

Ischemic heart disease is a leading cause of death, and there is considerable imperative to identify effective therapeutic interventions. Cardiomyocyte Ca2+ overload is a major cause of ischemia and reperfusion injury, initiating a cascade of events culminating in cardiomyocyte death, myocardial dysfunction, and occurrence of lethal arrhythmias. Responsive to fluctuations in intracellular Ca2+, Ca2+/calmodulin-dependent protein kinase II (CaMKII) has emerged as an enticing therapeutic target in the management of ischemic heart injury. CaMKII is activated early in ischemia and to a greater extent in the first few minutes of reperfusion, at a time when reperfusion arrhythmias are particularly prominent. CaMKII phosphorylates and upregulates many of the key proteins involved in intracellular Na+ and Ca2+ loading in ischemia and reperfusion. Experimentally, selective inhibition of CaMKII activity reduces cardiomyocyte death and arrhythmic incidence post-ischemia. New evidence is emerging that CaMKII actions in ischemia and reperfusion involve specific splice variant targeted actions, selective and localized post-translational modifications, and organelle-directed substrate interactions. A more complete mechanistic understanding of CaMKII mode of action in ischemia and reperfusion is required to optimize intervention opportunities. This review summarizes the current experimentally derived understanding of CaMKII participation in mediating the pathophysiology of the heart in ischemia and in reperfusion, and highlights priority future research directions.Centro de Investigaciones Cardiovasculare

Chlamydomonas DYX1C1/PF23 is essential for axonemal assembly and proper morphology of inner dynein arms

Cytoplasmic assembly of ciliary dyneins, a process known as preassembly, requires numerous non-dynein proteins, but the identities and functions of these proteins are not fully elucidated. Here, we show that the classical Chlamydomonas motility mutant pf23 is defective in the Chlamydomonas homolog of DYX1C1. The pf23 mutant has a 494 bp deletion in the DYX1C1 gene and expresses a shorter DYX1C1 protein in the cytoplasm. Structural analyses, using cryo-ET, reveal that pf23 axonemes lack most of the inner dynein arms. Spectral counting confirms that DYX1C1 is essential for the assembly of the majority of ciliary inner dynein arms (IDA) as well as a fraction of the outer dynein arms (ODA). A C-terminal truncation of DYX1C1 shows a reduction in a subset of these ciliary IDAs. Sucrose gradients of cytoplasmic extracts show that preassembled ciliary dyneins are reduced compared to wild-type, which suggests an important role in dynein complex stability. The role of PF23/DYX1C1 remains unknown, but we suggest that DYX1C1 could provide a scaffold for macromolecular assembly

Atmospheric drivers of melt-related ice speed-up events on the Russell Glacier in Southwest Greenland

The Greenland ice sheet is a major contributor to current and projected sea level rise in the warming climate. However, uncertainties in Greenland&rsquo;s contribution to future sea level rise remain, partly due to challenges in constraining the role of ice dynamics. One process that has the potential to indirectly affect the mass budget of the ice sheet are transient ice accelerations, or ice speed-up events, lasting from one day to a week and triggered by overloading the subglacial drainage system with an increase in water supply. In this study, we identify melt-induced ice speed-up events at the Russell Glacier, Southwest Greenland, in order to analyse synoptic patterns driving these events. The short-term speed-up events are identified from daily ice velocity time series collected from six GPS stations along the glacier, for each summer (May&ndash;September) from 2009 to 2012. In total, 45 ice speed-up events are identified, of which 36 are considered melt-induced events where melt is derived from two in-situ observational datasets and one regional climate model forced by ERA5 reanalysis. 16 out of the 45 speed-up events co-occur with lake drainage events, and only four are linked with extreme rainfall events. The 36 melt-induced speed-up events occur during synoptic patterns that can be grouped into three main clusters: (1) patterns that resemble atmospheric rivers with a landfall in Southwest Greenland, (2) patterns with anticyclonic blockings centred over Southwest Greenland, and (3) patterns that show low pressure systems centred either south or southeast of Greenland. Out of these clusters, the one resembling atmospheric river patterns is linked to the strongest speed-up events induced by a 2&ndash;3 day continuously increasing surface melt driven by anomalously high sensible heat flux and incoming longwave radiation. In the other two clusters, the net shortwave radiation dominates the contribution to the melt energy. As the frequency and intensity of these weather patterns may change in the warming climate, so may the frequency and intensity of ice speed-up events, ultimately altering the mass loss of the ice sheet.</p

Terminus-driven retreat of a major southwest Greenland tidewater glacier during the early 19th century : insights from glacier reconstructions and numerical modelling

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